On 14 October 2022, Science published the Research Article “In vivo direct imaging of neuronal activity at high temporospatial resolution” by P. T. Toi et al. (1). The editors have been made aware that the methods described in the paper are inadequate to allow reproduction of the results and that the results may have been biased by subjective data selection. We are alerting readers to these concerns while the authors provide additional methods and data to address the issues.
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