A tetramer of BCL11A is required for stable protein production and fetal hemoglobin silencing | Science

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Down-regulation of BCL11A protein reverses the fetal (HbF, α2γ2) to adult (HbA, α2β2) hemoglobin switch and is exploited in gene-based therapy for hemoglobin disorders. Because of reliance on ex vivo cell manipulation and marrow transplant, such …



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Tanya Pike spends most of her time writing about arts, automotive, travel and fashion. She also loves to read and watch movies. She is a huge fan of Celine Dion and has seen every movie she has acted in.

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